1 Timothy 5:17

• presbuteros (πρεσβύτερος, 4245), an adjective, the comparative degree of presbus, “an old man, an elder,” is used (a) of age (b) of rank or positions of responsibility
• proistemi (προΐστημι, 4291), lit., “to stand before,” hence, “to lead, attend to” (indicating care and diligence), is translated “to rule” (middle voice), with reference to a local church, in Rom. 12:8; perfect active in 1 Tim. 5:17; with reference to a family, 1 Tim. 3:4 and 12 (middle voice); v. 5 (2nd aorist, active)

A Guide, Lead (36.1–36.9)

• 36.1 ἡγέομαι^b; προί̈σταμαι^a; κατευθύνω; φέρω^d; ἄγω^d: to so influence others as to cause them to follow a recommended course of action—‘to guide, to direct, to lead.’ἡγέομαι^b : γινέσθω … ὁ ἡγούμενος ὡς ὁ διακονῶν ‘he who takes the lead must be like the one who serves’ or ‘he who is the master must be like one who serves’ Lk 22:26; μνημονεύετε τῶν ἡγουμένων ὑμῶν ‘remember your leaders’ or ‘… masters’ He 13:7.
• προί̈σταμαι^a: προϊσταμένους ὑμῶν ἐν κυρίῳ καὶ νουθετοῦντας ὑμᾶς ‘those who guide you in the Lord and instruct you’ 1 Th 5:12. The phrase ‘in the Lord’ probably refers to matters concerning the Christian life.
• κατευθύνω: ὁ δὲ κύριος κατευθύναι ὑμῶν τὰς καρδίας εἰς τὴν ἀγάπην τοῦ θεοῦ ‘may the Lord lead your hearts to the love for God’ 2 Th 3:5.φέρω^d: φερόμενοι ἐν τῷ ἁγίῳ πνεύματι ‘being guided by the Holy Spirit’ Ac 15:29 (apparatus); ἀλλὰ ὑπὸ πνεύματος ἁγίου φερόμενοι ἐλάλησαν ‘but being led by the Holy Spirit, they spoke’ 2 Pe 1:21
• kopiao (κοπιάω, 2872), akin to A, No. 1, has the two different meanings (a) “growing weary,” (b) “toiling”; it is sometimes translated “to bestow labor” (see under bestow, No. 3). It is translated by the verb “to labor” in Matt. 11:28; John 4:38 (2nd part); Acts 20:35; Rom. 16:12 (twice); 1 Cor. 15:10; 16:16; Eph. 4:28; Phil. 2:16; Col. 1:29; 1 Thess. 5:12; 1 Tim. 4:10; 5:17; 2 Tim. 2:6; Rev. 2:3; 1 Cor. 4:12, rv, “toil” (kjv, “labor”)